What Best Describes Smooth Muscle Cells
The smooth muscle cells of blood vessels display considerable plasticity in their phenotype. However during the life span of an individual vascular cells can switch to a synthetic largely noncontractile phenotype in response to proinflammatory stimuli diet or.
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Werner syndrome WS a premature aging condition in humans is caused.
. DNA strand breaks also increased in atherosclerotic plaques thus linking DNA damage to plaque formation. Atherosclerotic plaque contains vascular smooth muscle cells macrophages and endothelial cells and these have been found to accumulate 8-oxoG a common type of oxidative DNA damage. In healthy young blood vessels the phenotype is largely contractile and blood pressure is well autoregulated.
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